exposure

• 26 June 2013

  TR 119 – Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals

  TR 119 : Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals | 26 March 2013 Technical Report no.119. Evaluation of systemic […]

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  • Tags : (Q)SAR, ADME, Animal, Assessment, assessment tool, chemical safety, Chemicals, decision tree, derivation, dermal, Dermal absorption, dermal risk, exposure, Exposure assessment, initial risk characterization, legislation, non-animal, paint, pharmaceuticals, REACh, refined risk characterization, risk assesment, safety, studies, Toxicology
• 31 July 2012

  TR 115 – Effects of Chemical Co-exposures at Doses Relevant for Human Safety Assessments

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  • Tags : acid, acute, carcinogenicity, chemical, chemical regulation, chronic, component, concentration, developmental, dissimilar chemicals, dose, endocrine, environmental, exposure, in vitro, mammalian, melamine, Mixture, NOAEL, Oestrogen, organ, organic, pyrethrin, Risk assessment, safety margin, similar chemicals, substance, synergistic, testing, toxic, Toxicity, Toxicology, Treatment, Tumour
• 30 July 2012

  TR 114 – ECETOC TRA version 3: Background and Rationale for the Improvements

  TR 114 : ECETOC TRA version 3: Background and Rationale for the Improvements | 30 July 2012 SUMMARY The ECETOC Targeted Risk Assessment […]

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  • Tags : care products, Chemicals, Consumer, energy, environment, exposure, metal, Research, Risk assessment, safety, solvent, targeted risk assessment (TRA), Technical Guidance on Information Requirements and Chemicals Safety Assessment (IRCSA), Tier, worker
• 29 October 2011

  TR 112 – Refined Approaches for Risk Assessment of PBT/vPvB Chemicals

  TR 112 : Refined Approaches for Risk Assessment of PBT/vPvB Chemicals | October 2011 ISSN-0773-8072-112 (print) ISSN-2079-1526-112 (online) D-2011-3001-218 Summary Building upon a […]

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  • Tags : Assessment, Biomonitoring, chemical, Critical body burden approach (CBB), Ecological, environmental, Environmental exposure concentration (PEC), exposure, Exposure assessment, Food, food chain, Hazard, Kinetic, Methodology, Modelling technique, PBT chemicals, PBT/vPvB chemicals, Physico-chemical, PNEC, Predicted no effects concentration (PNEC), RAIDAR, Research, Risk assessment, Scientific, Secondary poisoning, substance, Toxicity, Toxicological, Uncertainty, Value
• 29 October 2011

  TR 111 – Development of guidance for assessing the impact of mixtures of chemicals in the aquatic environment

  TR 111 : Development of guidance for assessing the impact of mixtures of chemicals in the aquatic environment | October 2011 ISSN-0773-8072-111 (print) […]

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  • Tags : chemical, Chemical preparation, Composition, concentration, Consumer, Discharge, Ecotoxicology, Effluent, environment, environmental risk, exposure, Industrial activity, metal, Mixture, pharmaceuticals, Preparation, toxic
• 29 December 2010

  TR 110 – Guidance on Assessment Factors to Derive a DNEL

  TR 110 : Guidance on Assessment Factors to Derive a DNEL | Dec 2010 Executive Summary The European Regulation on the Registration, Evaluation, Authorisation […]

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  • Tags : Animal, Assessment, cancer, chemical, Chemical safety assessments (CSA), chronic effects, chronic exposure, Compound, default AF, derived no-effect levels (DNEL), exposure, exposure scenarios (ES), Food, general population, health, Informed AF, inhalation, irritation, local effect, Lung, R.8 guidance, REACh, REACH TGD, safety assessment, skin contact, systemic effect, targeted risk assessment (TRA), Treatment, workplace
• 29 December 2009

  TR 108 – Collation of Existing Marine Biodegradation Data and its Use in Environmental Risk Assessment [Includes EMBK Database]

  TR 108 : Collation of Existing Marine Biodegradation Data and its Use in Environmental Risk Assessment | December 2009 The primary focus for […]

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  • Tags : abiotic, analysis, aquatic system, biodegradation, biodegradation screening test, biotic, chemical, concentration, default, degradable, degradation, degradation potential, ecotoxicological, environmental, Environmental risk assessment, estuarine, exposure, Exposure assessment, extrapolation, factor, Freshwater, half-lives, hazardous substances, identity, inoculum source, kinetic data, marine environment, purity, quality control, REACh, screening, study, test data, Toxicological
• 29 December 2009

  TR 107 – Addendum to ECETOC Targeted Risk Assessment Technical Report No. 93

  TR 107 : Addendum to ECETOC Targeted Risk Assessment Technical Report No. 93 | December 2009 The ECETOC targeted risk assessment (TRA) Task […]

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  • Tags : approach, chemical safety assessment, consumer health risk, CSA/CSR, Ecetoc, ECHA, environmenmtal risk assessment, environment, exposure, high energy conditions, metal, organic chemicals, paint, product, recommandation, risk management, Scientific, soil, tool, TRA, worker health risk
• 29 January 2009

  TR 104 – Framework for the Integration of Human and Animal Data in Chemical Risk Assessment

  TR 104 : Framework for the Integration of Human and Animal Data in Chemical Risk Assessment | January 2009 Human data form the […]

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  • Tags : Animal, animal data, approach, cancer, chemical, exposurchemical, exposure, Framework, health effect, human data, Human health, pharmaceuticals, Population, Risk, Risk assessment, task force, Toxicological
• 28 July 2008

  Workshop Report 11 – Workshop on the Application of ‘Omics in Toxicology and Ecotoxicology: Case Studies and Risk Assessment

  WR 11 : Workshop on the Application of ‘Omics in Toxicology and Ecotoxicology: Case Studies and Risk Assessment | July 2008 To review […]

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  • Tags : biological, cellular, chemical, chemical risk, chemical safety, Chemical substances, chronic, control, ecological risk assessment, environment, environmental, exposure, fish, gene expression, genomic science, genomics data, guidance, Industry, NOAEL, omic, organism, parameter, pathway, Pharmaceutical, pharmaceutical industry, Population, profile, Risk assessment, science, scientist, standard, study, technology, Toxicant, Toxicity, Toxicology, Tumour