developmental toxicity

• 26 August 2014

  Incorporating potency into EU classification for carcinogenicity and reproductive toxicity

  Although risk assessment, assessing the potential harm of each particular exposure of a substance, is desirable, it is not feasible in many situations. […]

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  • Tags : carcinogenicity, Classification, Degree of hazard, developmental toxicity, Hazard communication, potency, Reproductive toxicity
• 28 September 2007

  JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.II

  JACC 053 Vol II : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I […]

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  • Tags : 1 1-dichloroethylene, 1 1-Difluoroethane, Acute toxicity, adrenaline, Allergy, American Industrial Hygiene Association, Ames test, Aquatic organisms, Atmospheric degradation, BHK21, Cardiac sensitisation, Chlorofluorocarbon, chromatography, chromosomal aberration, CO2, developmental toxicity, Ecotoxicity, environment, environmental toxicity, exposure, flammable colourless gas, formaldehyde, Genomics, genotoxic potential, global warming potential, HF, HFC, HFC-143a, Human volunteers, in vitro, in vivo, inhalation, lymphocytes, metabolite, method of exposure, NOAEL, occupational exposure., Ozone depletion, PAFT, physico-chemical properties, rabbit, rats, Refrigeration systems, reproductive effects, Salmonella typhimurium, Sex, stratospheric ozone layer, Styles Assay, testicular weight, Toxicity, Toxicology, trifluoroacetaldehyde, Trifluoroethane, Trifluoroethanol, volatilise, whole-body
• 28 September 2007

  JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.I

  JACC 053 Vol I : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I […]

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  • Tags : 1 1-dichloroethylene, 1 1-Difluoroethane, Acute toxicity, adrenaline, Allergy, American Industrial Hygiene Association, Ames test, Aquatic organisms, Atmospheric degradation, BHK21, Cardiac sensitisation, Chlorofluorocarbon, chromatography, chromosomal aberration, CO2, developmental toxicity, Ecotoxicity, environment, environmental toxicity, exposure, flammable colourless gas, formaldehyde, Genomics, genotoxic potential, global warming potential, HF, HFC-143a, Human volunteers, in vitro, in vivo, inhalation, lymphocytes, metabolite, method of exposure, NOAEL, occupational exposure., Ozone depletion, PAFT, physico-chemical properties, rabbit, rats, Refrigeration systems, reproductive effects, Salmonella typhimurium, Sex, stratospheric ozone layer, Styles Assay, testicular weight, Toxicity, Toxicology, trifluoroacetaldehyde, Trifluoroethane, Trifluoroethanol, volatilise, whole-body
• 28 September 2006

  JACC Report 51 – Synthetic Amorphous Silica

  JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity […]

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  • Tags : Absorption, acute inhalation toxicity, adverse effects, agglomerates, airborne concentrations, alkali metal silicate, American Conference for Governmental Industrial Hygienists, amorphous silicas, aqueous systems, bioavailable, bone marrow, cancer, carcinogenicity, chromatography, chromosomal aberrations, chronic toxicity, Condensation, contact allergy, cosmetics, cracking, dermal irritation, dermal toxicity, developmental toxicity, diatoms, dichlorodimethyl, DNA synthesis, dryness, Ecotoxicology, elastomers, Emphysema, environment, Environmental fate, Epidemiology, Erythema, Excreted, experimental animals, eye irritant, Eye Irritation, fertility, focal fibrosis, Gas chromatography, genotoxic, Genotoxicity, granuloma, human risk assessment, Hydrophilic, hydrophobic, in vitro, in vivo, inhalable, inhalation, inks, International Agency for Research on Cancer, Intravenous injection, intrinsic toxicity, LOAEL, Long-term inhalation, long-term respiratory health effects, lung collagen, lung collagen content, lung inflammation. lung tumours, man-made SAS, mechanical irritation, methyl, mice, Morphology, mortality, mutagenic, natural flux, neoplasms, NOAEL, non-crystalline, non-toxic, oral, oral administration, particle size, peripheral, pharmaceuticals, pneumonia, precipitated silica, pulmonary function, pulmonary inflammation, pulmonary retention, pyrogenic silica, rats, reproductive organs, respirable, respiratory distress, SAS, SAS dust, Sex, Silica, silica gel, Silicon dioxide, silicon metal, Skin Irritation, sodium chloride, solubility, spectroscopy, subchronic, subcutaneously, Suffocation, surface treatment, survival rate, synthetic amorphous silica, thermal route, tissue reaction, toxic, Toxicology, tumours, weight gain, wet route
• 28 September 2005

  JACC Report 48 – Hexafluoropropylene

  JACC 048 : Hexafluoropropylene (CAS No. 116-15-4) | October 2005 This report has been produced as part of the ECETOC Joint Assessment of […]

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  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, atmospheric breakdown, bioaccumulate, biota, cancer, carbon dioxide, carcinogenicity, chronic toxicity, clonic spasms, closed systems, consumer exposure, developmental toxicity, developmental toxicity studies, DNA synthesis, Ecotoxicity, environment, environmental risk, exposure limit, fluoro-elastomers, Fluoropolymers, Genotoxicity, German MAK Commission, global warming, Hexafluoropropylene, HFP, hydrogen fluoride, kidney, mice, nephrotoxicity, NOAEL, occupational exposure., partition, perfluoropolyether functional fluids, photolysis, polymeric products, rats, reaction, relative kidney weight, relative spleen weight, reproductive system, Soluble, Synthesis, target organ, Tetrafluoroethylene, Toxicity, trifluoroacetic acid
• 28 May 2005

  JACC Report 47 – 1,1-Dichloro-2,2,2-trifluoroethane (HCFC-123) Third edition

  JACC 047 : 1,1-Dichloro-2,2,2-trifluoroethane (HCFC-123)CAS No. 306-83-2 (Third Edition) | July 2005 This report has been produced as part of the ECETOC Joint […]

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  • Tags : air levels, air-conditioning, algae, Aquatic organisms, Aquatic toxicity, benign tumours, bio-concentrate, Biodegradable, body weight gain, cardiac arrhythmia, cell transformation, central nervous system, chromosome aberration, Clastogenic activity, CNS, concurrent exposure, Copenhagen Amendment, Depression, developmental toxicity, Dichloro-2 2 2-trifluoroethane, dogs, exposure groups, Eye Irritation, fish, genotoxic, global warming potential, Growth, guinea pigs, hamster, HCFC-123, HCFC-124, hepatic, hepatocellular adenomas, HFC-125, hormonal disturbances, human exposure, human lymphocytes, hygiene practices, immuno-blotting, in vivo, lesions, life threatening, liver disease, liver lesions, LOAEL, lower body weight, Montreal Protocol, necrosis, neonates, occupational exposure., peroxisome proliferation, proliferation, rabbits, radicals, Rat, Refrigerant, reproductive performance, Soluble, strain, testicular tumours, Tetrachloroethylene, toxic, trifluoroacetic acid, trifluoroacetyl chloride, β-oxidation
• 29 March 2005

  TR 095 Vol II – The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume II – Substance Profiles

  TR 095 Vol II : The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume II – Substance Profiles | […]

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  • Tags : anaemia, apoptosis, carcinogenicity, carcinogenicity studies, Dermal absorption, dermal applications, developmental effects, developmental toxicity, DNA synthesis, dose groups, ethylene and propylene glycol mono-ethers and di-ethers, ethylene-based glycol ethers, genotoxic activity, Genotoxicity, Glycol mono-ethers, granulocytopenia, haematological effects, haemolytic effects, Kavlock protocol, leukopenia, oral dosing, Propylene glycol, Skin Irritation, solvent applications, Systemic toxicity, testicular atrophy, toxicity data, treatment groups
• 29 November 2004

  Workshop Report 04 – Influence of Maternal Toxicity in Studies on Developmental Toxicity

  WR 04 : Influence of Maternal Toxicity in Studies on Developmental Toxicity | October 2004 The Workshop was convened to explore whether the […]

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  • Tags : body weight, breakout groups, chemical administration, chemical exposure, Chemicals, developmental effects, developmental toxicity, embryo/foetus, gavage, hazard identification, human exposure, maternal homeostasis, maternal organism, mode of administration, OECD, OECD 414 test guideline, oral bolus, Pregnancy, Recommendations, Reproductive toxicity, risk characterisation, route of administration, toxic effects, toxicodynamics, toxicokinetics
• 28 February 2002

  Monograph 031 – Guidance on Evaluation of Reproductive Toxicity Data

  Mono 031 : Guidance on Evaluation of Reproductive Toxicity Data | February 2002 The reproductive process is complex and there are many stages […]

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  • Tags : anophthalmia, artificial insemination, developmental neurotoxicity, developmental toxicity, developmental toxicity studies, exencephaly, fertility, Hazard assessment, Maternal toxicity, reproductive process, reproductive system, Reproductive toxicity, reproductive toxicity data, Toxicity