carcinogenicity

• 26 August 2014

  Incorporating potency into EU classification for carcinogenicity and reproductive toxicity

  Although risk assessment, assessing the potential harm of each particular exposure of a substance, is desirable, it is not feasible in many situations. […]

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  • Tags : carcinogenicity, Classification, Degree of hazard, developmental toxicity, Hazard communication, potency, Reproductive toxicity
• 31 July 2012

  TR 115 – Effects of Chemical Co-exposures at Doses Relevant for Human Safety Assessments

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  • Tags : acid, acute, carcinogenicity, chemical, chemical regulation, chronic, component, concentration, developmental, dissimilar chemicals, dose, endocrine, environmental, exposure, in vitro, mammalian, melamine, Mixture, NOAEL, Oestrogen, organ, organic, pyrethrin, Risk assessment, safety margin, similar chemicals, substance, synergistic, testing, toxic, Toxicity, Toxicology, Treatment, Tumour
• 28 December 2011

  JACC Report 55 – Linear Polydimethylsiloxanes second edition

  JACC 055 : Linear Polydimethylsiloxanes CAS No. 63148-62-9 (Second Edition) | December 2011 ISSN-0773-6339-55 print ISSN-2079-1496-55 online D-2011-3001-220 EXECUTIVE SUMMARY This report presents […]

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  • Tags : Adsorption, Aquatic organisms, Autoimmune disorders, Breast cancer, Breast implant, cancer, carbon dioxide, carcinogenicity, Dermal contact, Dermatology, Dimethylsilanediol, DMSD, European Union, Extraction efficiency, fibromyalgia, Gas chromatography, Heat transfer, Human health, hydrophobic chemicals, in vitro, in vivo, Inorganic silicate, Insects, Insoluble, Linear polydimethylsiloxanes, mammaplasty, MS, muscular rheumatism, mutagenic, Mutagenic activity, Non-volatile, Occupational exposure limit, OECD, Ophthalmological problems, Oral ingestion, pharmaceutical applications, Polydimethylsiloxane, Radiation, rheumatic disease, rheumatoid arthritis, sarcomas, Sewage treatment, silicone oil, Silicones, Skin irritant, skin sensitiser, Soil organisms, sorption, spectroscopy, Swallowed PDMS, Toxicity, Toxicology, Urological problems, US FDA, wastewater treatment
• 28 September 2006

  JACC Report 51 – Synthetic Amorphous Silica

  JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity […]

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  • Tags : Absorption, acute inhalation toxicity, adverse effects, agglomerates, airborne concentrations, alkali metal silicate, American Conference for Governmental Industrial Hygienists, amorphous silicas, aqueous systems, bioavailable, bone marrow, cancer, carcinogenicity, chromatography, chromosomal aberrations, chronic toxicity, Condensation, contact allergy, cosmetics, cracking, dermal irritation, dermal toxicity, developmental toxicity, diatoms, dichlorodimethyl, DNA synthesis, dryness, Ecotoxicology, elastomers, Emphysema, environment, Environmental fate, Epidemiology, Erythema, Excreted, experimental animals, eye irritant, Eye Irritation, fertility, focal fibrosis, Gas chromatography, genotoxic, Genotoxicity, granuloma, human risk assessment, Hydrophilic, hydrophobic, in vitro, in vivo, inhalable, inhalation, inks, International Agency for Research on Cancer, Intravenous injection, intrinsic toxicity, LOAEL, Long-term inhalation, long-term respiratory health effects, lung collagen, lung collagen content, lung inflammation. lung tumours, man-made SAS, mechanical irritation, methyl, mice, Morphology, mortality, mutagenic, natural flux, neoplasms, NOAEL, non-crystalline, non-toxic, oral, oral administration, particle size, peripheral, pharmaceuticals, pneumonia, precipitated silica, pulmonary function, pulmonary inflammation, pulmonary retention, pyrogenic silica, rats, reproductive organs, respirable, respiratory distress, SAS, SAS dust, Sex, Silica, silica gel, Silicon dioxide, silicon metal, Skin Irritation, sodium chloride, solubility, spectroscopy, subchronic, subcutaneously, Suffocation, surface treatment, survival rate, synthetic amorphous silica, thermal route, tissue reaction, toxic, Toxicology, tumours, weight gain, wet route
• 29 July 2006

  TR 099 – Toxicological Modes of Action: Relevance for Human Risk Assessment

  TR 099 : Toxicological Modes of Action: Relevance for Human Risk Assessment | July 2006 Generally, the assessment of hazard and risk to […]

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  • Tags : assessment factors, carcinogenicity, Carcinomas, chemical carcinogenesis, chronic exposure, default approach, Ecotoxicology, experimental animals, forestomach tumours, human risk assessment, irritation, mode of action, molecular and cellular processes, Pharmacokinetics, toxic effect, toxic endpoint, Toxicity, toxicokinetics, Toxicology
• 28 September 2005

  JACC Report 48 – Hexafluoropropylene

  JACC 048 : Hexafluoropropylene (CAS No. 116-15-4) | October 2005 This report has been produced as part of the ECETOC Joint Assessment of […]

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  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, atmospheric breakdown, bioaccumulate, biota, cancer, carbon dioxide, carcinogenicity, chronic toxicity, clonic spasms, closed systems, consumer exposure, developmental toxicity, developmental toxicity studies, DNA synthesis, Ecotoxicity, environment, environmental risk, exposure limit, fluoro-elastomers, Fluoropolymers, Genotoxicity, German MAK Commission, global warming, Hexafluoropropylene, HFP, hydrogen fluoride, kidney, mice, nephrotoxicity, NOAEL, occupational exposure., partition, perfluoropolyether functional fluids, photolysis, polymeric products, rats, reaction, relative kidney weight, relative spleen weight, reproductive system, Soluble, Synthesis, target organ, Tetrafluoroethylene, Toxicity, trifluoroacetic acid
• 29 March 2005

  TR 095 Vol II – The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume II – Substance Profiles

  TR 095 Vol II : The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume II – Substance Profiles | […]

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  • Tags : anaemia, apoptosis, carcinogenicity, carcinogenicity studies, Dermal absorption, dermal applications, developmental effects, developmental toxicity, DNA synthesis, dose groups, ethylene and propylene glycol mono-ethers and di-ethers, ethylene-based glycol ethers, genotoxic activity, Genotoxicity, Glycol mono-ethers, granulocytopenia, haematological effects, haemolytic effects, Kavlock protocol, leukopenia, oral dosing, Propylene glycol, Skin Irritation, solvent applications, Systemic toxicity, testicular atrophy, toxicity data, treatment groups
• 28 May 1998

  Special Report 14 – n-Butyl Methacrylate Isobutyl Methacrylate OEL Criteria Document

  SR 14 : n-Butyl Methacrylate and Isobutyl Methacrylate OEL Criteria Document | May 1998

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  • Tags : Butyl methacrylate, carcinogenicity, Chemical agent, Chemical group, chemical properties, Chemical reactivity, Co-monomer, Eco-toxicology, Hydrolysis, irritation, Isobutyl methacrylate, Isomers, Monomer, occupational exposure., Polymer formation, Psycho-chemical data, Radioactivity, Risk assessment, Sensitisation, Toxicological data, Toxicology