Animal

• 26 June 2013

  TR 119 – Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals

  TR 119 : Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals | 26 March 2013 Technical Report no.119. Evaluation of systemic […]

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  • Tags : (Q)SAR, ADME, Animal, Assessment, assessment tool, chemical safety, Chemicals, decision tree, derivation, dermal, Dermal absorption, dermal risk, exposure, Exposure assessment, initial risk characterization, legislation, non-animal, paint, pharmaceuticals, REACh, refined risk characterization, risk assesment, safety, studies, Toxicology
• 29 December 2010

  TR 110 – Guidance on Assessment Factors to Derive a DNEL

  TR 110 : Guidance on Assessment Factors to Derive a DNEL | Dec 2010 Executive Summary The European Regulation on the Registration, Evaluation, Authorisation […]

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  • Tags : Animal, Assessment, cancer, chemical, Chemical safety assessments (CSA), chronic effects, chronic exposure, Compound, default AF, derived no-effect levels (DNEL), exposure, exposure scenarios (ES), Food, general population, health, Informed AF, inhalation, irritation, local effect, Lung, R.8 guidance, REACh, REACH TGD, safety assessment, skin contact, systemic effect, targeted risk assessment (TRA), Treatment, workplace
• 29 January 2009

  TR 104 – Framework for the Integration of Human and Animal Data in Chemical Risk Assessment

  TR 104 : Framework for the Integration of Human and Animal Data in Chemical Risk Assessment | January 2009 Human data form the […]

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  • Tags : Animal, animal data, approach, cancer, chemical, exposurchemical, exposure, Framework, health effect, human data, Human health, pharmaceuticals, Population, Risk, Risk assessment, task force, Toxicological
• 29 October 2006

  TR 101 – Guidance for setting occupational exposure limits: Emphasis on data-poor substances

  TR 101 : Guidance for setting occupational exposure limits: Emphasis on data-poor substances | October 2006 In the absence of sound human exposure […]

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  • Tags : air concentrations, air-water partition coefficient, Animal, animal data, Carcinogenic, chemical food contaminants, chemical properties, chemical safety assessment, chemical safety report, chemical substance, chronic, concentration, distributionexpert, exposed, exposure, hazard banding, hazard categories, health, homologous, human data, hydrocarbon, inhalation, integration, Lethal, Liquid, LOAEL, mammalian, Method, MTD, mutagenic, NOAEL, NTP, Occupational exposure limit (OEL), octanol-air partition coefficient, oral, overexposure, person, procedure, progeny, protection, public health risk, REACh, read-across approach, reprotoxic, respiratory dose, risk assessor, risk phrase, scientist, sensory irritation, solid, solvent, studies, substance, targeted risk, toxic, Toxicity, Toxicological, worker, workplace