2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme! ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why? Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
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Publications

Workshop Report no.35 – Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels
Workshop Report

Workshop Report no.35 – Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels

WR 35 Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels Published March 2018 ISSN-2078-7219-35 (online) D-2018-3001-253...
Workshop Report no.31: Advances in Consumer Exposure Science: Data, Modelling and Aggregate Exposure Assessment. 26th January 2016, Brussels
Workshop Report

Workshop Report no.31: Advances in Consumer Exposure Science: Data, Modelling and Aggregate Exposure Assessment. 26th January 2016, Brussels

This workshop report summarises a workshop held in Brussels on 26th January 2016 by the ECETOC Human Exposure Data Task Force on the state of the art of consumer exposure assessment science as develop...
TR 124 – Addendum to TR114 : Technical Basis for the TRA v3.1
Technical Report

TR 124 – Addendum to TR114 : Technical Basis for the TRA v3.1

TR124: Addendum to TR114 : Technical Basis for the TRA v3.1 Newsflash: In response to feedback received from users of the TRA, ECETOC has further improved the consumer portion of the model by the in...
Evaluation of systemic health effects following dermal exposure to chemicals
Technical Report

Evaluation of systemic health effects following dermal exposure to chemicals

Technical Report no.119. Evaluation of systemic health effects following dermal exposure to chemicals ISSN-0773-8072-119 (print) ISSN-2079-1526-119 (online) D-2013-3001-227 Science Newsflash...
Technical Report

TR 121 – Efficacy and safety of antidotes for acute poisoning by cyanides

TR 121 : Efficacy and safety of antidotes for acute poisoning by cyanides | 19 November 2013 SCIENCE NEWS FLASH: New ECETOC report offers guidance on the efficacy and safety of antidotes for acute p...
Technical Report

TR 119 – Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals

TR 119 : Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals | 26 March 2013 Technical Report no.119. Evaluation of systemic health effects following dermal exposure to che...
Technical Report

TR 114 – ECETOC TRA version 3: Background and Rationale for the Improvements

TR 114 : ECETOC TRA version 3: Background and Rationale for the Improvements | 30 July 2012 SUMMARY The ECETOC Targeted Risk Assessment (TRA) tool was launched in 2004. The TRA consists of 3 separat...
Workshop Report

Workshop Report 22 – Workshop on Combined Exposure to Chemicals

WR 22 : Workshop on Combined Exposure to Chemicals | October 2011 Workshop on Combined Exposure to Chemicals. 11-12 July 2011, Berlin Published October 2011 ISSN-2078-7200-22 (print) ISSN-2078...
Technical Report

TR 107 – Addendum to ECETOC Targeted Risk Assessment Technical Report No. 93

TR 107 : Addendum to ECETOC Targeted Risk Assessment Technical Report No. 93 | December 2009 The ECETOC targeted risk assessment (TRA) Task Force reported in 2004 (Technical Report No. 93), and launc...
Workshop Report

Workshop Report 14 – Use of Markers for Improved Retrospective Exposure Assessment in Epidemiology Studies

WR 14 : Use of Markers for Improved Retrospective Exposure Assessment in Epidemiology Studies | February 2009 The workshop addressed the question of whether new analytical and molecular techniques...
JACC

JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.I

JACC 053 Vol I : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I and II | November 2007 This report has been produce...
Technical Report

TR 101 – Guidance for setting occupational exposure limits: Emphasis on data-poor substances

TR 101 : Guidance for setting occupational exposure limits: Emphasis on data-poor substances | October 2006 In the absence of sound human exposure data, existing procedures for setting occupational e...
Technical Report

TR 100 – Contribution to the Methodology for the Development of Acute Exposure Threshold Levels in Case of Accidental Chemical Release

TR 100 : Contribution to the Methodology for the Development of Acute Exposure Threshold Levels in Case of Accidental Chemical Release | July 2006 The ACUTEX project was a three-year research activit...
Technical Report

TR 097 – Alternative Testing Approaches in Environmental Safety Assessment

TR 097 : Alternative Testing Approaches in Environmental Safety Assessment | January 2006 There are many opportunities for applying the principles of the three Rs (replacement, reduction and refineme...
Document

DOC 044 – Guidance for the Interpretation of Biomonitoring Data

DOC 044 : Guidance for the Interpretation of Biomonitoring Data | November 2005 Measuring the levels of chemical substances in human body fluids and tissues has been in routine use in industry and...

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