read-across

• 12 November 2013

  A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

  Highlights ? Alternatives are yet only available for acute fish toxicity testing.? Limited access to animal test data hinders the development of alternatives.? […]

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  • Tags : (Q)SAR, 3Rs, Acute toxicity, Bioconcentration, Cell lines, chronic toxicity, endocrine disruption, Exposure-based waiving, Fish embryo test, read-across
• 28 June 2013

  Use of category approaches, read-across and (Q)SAR: General considerations

  Read-across has generated much attention since it may be used as an alternative approach for addressing the information requirements under regulatory programmes, notably […]

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  • Tags : (Q)SAR, Analogue approach, Category approach, Data gap filling, Ecetoc, REACh, read-across
• 21 November 2012

  TR 116 – Category approaches, read-across, (Q)SAR

  TR 116 : Category approaches, read-across, (Q)SAR | 21 November 2012 Background An accepted practice for the assessment of human health and environmental […]

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  • Tags : (Q)SAR, analogue, approach, Assessment, category, Ecotoxicity, environmental, experimental, expert, generic, in vitro, in vivo test, Industry, mammalian, metal, narcotic, non-testing approach, organic, PBPK, product, REACh, read-across, Risk assessment, safety, skin, studies, target chemicals, toxic, Toxicity
• 29 December 2010

  TR 109 – High information content technologies in support of read-across in chemical risk assessment

  TR 109 : High information content technologies in support of read-across in chemical risk assessment | December 2010 Read-across exploits information on structurally […]

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  • Tags : analogue identification, chemical, chemical categories, chemical grouping, chemical reaction, Chemical reactivity, chemical risk assessment, data mining, Database, environmental, Heuristics, Hypotheses, hypothesis, mechanism of action, metabolomics, oestrogens, phthalates, read-across, skin sensitisers., target chemical, Toxicity, toxicogenomics, Toxicological
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  29 January 2006

  TR 097 – Alternative Testing Approaches in Environmental Safety Assessment

  TR 097 : Alternative Testing Approaches in Environmental Safety Assessment | January 2006 There are many opportunities for applying the principles of the […]

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  • Tags : (Q)SAR, Absorption, algae, animal testing, bioconcentration of chemicals, biomagnification, Biomimetic extraction, cellular systems, chemical biotransformation, chronic effects, daphnids, Ecotoxicology, endocrine activity, Environmental risk assessment, environmental safety, excretion, exposure concentration, fish cell line, in vitro systems, Metabolism, read-across, sorption, step-down approach, toxicogenomics