irritation

• 29 December 2010

  TR 110 – Guidance on Assessment Factors to Derive a DNEL

  TR 110 : Guidance on Assessment Factors to Derive a DNEL | Dec 2010 Executive Summary The European Regulation on the Registration, Evaluation, Authorisation […]

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  • Tags : Animal, Assessment, cancer, chemical, Chemical safety assessments (CSA), chronic effects, chronic exposure, Compound, default AF, derived no-effect levels (DNEL), exposure, exposure scenarios (ES), Food, general population, health, Informed AF, inhalation, irritation, local effect, Lung, R.8 guidance, REACh, REACH TGD, safety assessment, skin contact, systemic effect, targeted risk assessment (TRA), Treatment, workplace
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  28 December 2010

  Workshop Report 20 – Workshop on Guidance on Assessment Factors to Derive a DNEL

  WR 20 : Workshop on Guidance on Assessment Factors to Derive a DNEL | December 2010  Executive Summary Under REACH, chemicals produced in […]

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  • Tags : breakout groups, Breakout sessions, chemical risk assessment, chemical safety assessment, Derived no-effect level, DNEL, Hazard assessment, irritation, Negative human data, Point estimate, REACh, Risk assessment, SCOEL, Toxicology
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  29 July 2006

  TR 099 – Toxicological Modes of Action: Relevance for Human Risk Assessment

  TR 099 : Toxicological Modes of Action: Relevance for Human Risk Assessment | July 2006 Generally, the assessment of hazard and risk to […]

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  • Tags : assessment factors, carcinogenicity, Carcinomas, chemical carcinogenesis, chronic exposure, default approach, Ecotoxicology, experimental animals, forestomach tumours, human risk assessment, irritation, mode of action, molecular and cellular processes, Pharmacokinetics, toxic effect, toxic endpoint, Toxicity, toxicokinetics, Toxicology
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  28 January 2006

  JACC Report 50 – 1,1,1,2-Tetrafluoroethane (HFC-134a) Second edition

  JACC 050 : 1,1,1,2-Tetrafluoroethane (HFC-134a) (CAS No. 811-97-2) (Second Edition) | January 2006 This report has been produced as part of the ECETOC […]

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  • Tags : 1 1 1 2-Tetrafluoroethane, Acute toxicity, adrenaline, adverse effects, air-conditioning, aquatic environment, Aquatic organisms, atmospheric concentration, Atmospheric degradation, atmospheric lifetime, bioaccumulation, biodegradation, biota, body weight gain, bromine, carbon dioxide, Cardiac sensitisation, cell adenoma, chemical, chemical properties, chlorine, Chlorofluorocarbon, chronic toxicity, control groups, corn oil, degradation, DNA synthesis, Ecotoxicity, environment, Environmental fate, Epinephrine, experimental animals, expired air, Eye Irritation, female rats, fertility, formic acid, gas, genotoxic, global warming potential, greenhouse effect, haematology, HFC-134a, hydrochlorofluorocarbons, hydrofluoric acid, hydroxyl radicals, hyperplasia, in vitro, in vivo, inhalation, irritation, male rats, Metabolism, metered dose inhalers, non flammable gas, non-neoplastic, occupational exposure., Ozone depletion, PAFT, partition, Programme for Alternative Fluorocarbon Toxicity Testing, Propellants, rats, Refrigeration, reproductive effects, Sex, Skin Irritation, Skin sensitisation, skin sensitiser, soil, sorption, spectroscopy, teratogenic, testicular Leydig, testicular Leydig cell hyperplasia, testosterone, Toxicity, trifluoroacetic acid, Troposphere, tumours
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  28 February 2005

  Workshop Report 05 – Alternative Testing Approaches in Environmental Risk Assessment

  WR 05 : Alternative Testing Approaches in Environmental Risk Assessment | February 2005 This 2-day workshop, sponsored and organised by ECETOC, co-sponsored by […]

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  • Tags : action plan, angiosarcoma, case reports, chemical industry, chemical risk assessment, chemical safety, clear framework, data quality, epidemiological studies, European Commission’s Institute of Health and Consumer Protection, existing information sources, exposure, good exposure assessment practice, good human data collection practice, good risk assessment practice, human data, IHCP, International Programme on Chemical Safety, IPCS, irritation, null epidemiologic data, OECD, poisons centre records, Risk assessment, self-administered surveys, Use of Human Data in Risk Assessment
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  28 December 2003

  Special Report 17 – Risk Assessment Report for Existing Substances Methyl tertiary-Butyl Ether

  SR 17 : Risk Assessment Report for Existing Substances Methyl tertiary-Butyl Ether | December 2003 Methyl tertiary-butyl ether (MTBE) has been prioritised for […]

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  • Tags : Absorption, Antibodies, bioaccumulation, Biodegradable, carcinogen, chemical intermediate, chemical synthesis, chronic toxicity, CNS depression, DNA synthesis, dose groups, Ethyl tert-butyl ether, existing substances, exposure, follicular cell adenoma, formaldehyde, Gas chromatography, Genotoxicity, hepatocellular adenoma, human health risk assessment, irritation, Isobutylene, leukaemia, Liquid, Methyl tert-butyl ether, methyl tertiary butyl, methyl tertiary-Butyl Ether, organic chemicals, oxygenated gasoline, physico-chemical properties, pulmonary elimination, Risk assessment, risk reduction measures, sensory irritation, test protocol, toxicokinetics, treatment groups, vapour recovery systems, wastewater treatment
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  28 September 1998

  JACC Report 37 – Methyl Acrylate

  JACC 037 : Methyl Acrylate (CAS No.96-33-3) | September 1998 This report presents a critical evaluation of the toxicology and ecotoxicology of methyl […]

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  • Tags : Acrylic acid, Acute toxicity, allergic contact dermatitis, Atrophy opacification, Biodegradable, Clastogenic, Coatings, commodity chemicals, Cross-reactivity, Dehydrogenase pathway, Dermal absorption, dermatitis, Ethyl acrylate, Eye Irritation, Genotoxicity, GHS, Glutathione, Hydrolyse, Intraperitoneal injection, Irration corrosion, irritation, Lethargy, Liquid, Low acute toxicity, MA, Methacrylate, Methyl acrylate, Monomer, OECD, Organic solvents, Peroxidative pathway, Plastic additives, Polyacrylic fibres, Propionate degradation pathway, Pseudomonas, Radioactivity, Raw material, Reproductive risk, Respiratory Tract Irritation, Skin Irritation, Skin sensitisation, Synthesis, Systemic toxicity, Thioethers, tumours, Varnishes, Volatilisation
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  28 May 1998

  Special Report 14 – n-Butyl Methacrylate Isobutyl Methacrylate OEL Criteria Document

  SR 14 : n-Butyl Methacrylate and Isobutyl Methacrylate OEL Criteria Document | May 1998

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  • Tags : Butyl methacrylate, carcinogenicity, Chemical agent, Chemical group, chemical properties, Chemical reactivity, Co-monomer, Eco-toxicology, Hydrolysis, irritation, Isobutyl methacrylate, Isomers, Monomer, occupational exposure., Polymer formation, Psycho-chemical data, Radioactivity, Risk assessment, Sensitisation, Toxicological data, Toxicology