cancer

• 27 April 2014

  Epigenetic profiles as defined signatures of xenobiotic exposure 27 April 2014

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  • Tags : 5-hydroxymethylcytosine, 5-methylcytosine, 5hmC, 5mC, cancer, chemical safety, DNA methylation, Epigenetics
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  28 December 2011

  JACC Report 55 – Linear Polydimethylsiloxanes second edition

  JACC 055 : Linear Polydimethylsiloxanes CAS No. 63148-62-9 (Second Edition) | December 2011 ISSN-0773-6339-55 print ISSN-2079-1496-55 online D-2011-3001-220 EXECUTIVE SUMMARY This report presents […]

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  • Tags : Adsorption, Aquatic organisms, Autoimmune disorders, Breast cancer, Breast implant, cancer, carbon dioxide, carcinogenicity, Dermal contact, Dermatology, Dimethylsilanediol, DMSD, European Union, Extraction efficiency, fibromyalgia, Gas chromatography, Heat transfer, Human health, hydrophobic chemicals, in vitro, in vivo, Inorganic silicate, Insects, Insoluble, Linear polydimethylsiloxanes, mammaplasty, MS, muscular rheumatism, mutagenic, Mutagenic activity, Non-volatile, Occupational exposure limit, OECD, Ophthalmological problems, Oral ingestion, pharmaceutical applications, Polydimethylsiloxane, Radiation, rheumatic disease, rheumatoid arthritis, sarcomas, Sewage treatment, silicone oil, Silicones, Skin irritant, skin sensitiser, Soil organisms, sorption, spectroscopy, Swallowed PDMS, Toxicity, Toxicology, Urological problems, US FDA, wastewater treatment
• 29 December 2010

  TR 110 – Guidance on Assessment Factors to Derive a DNEL

  TR 110 : Guidance on Assessment Factors to Derive a DNEL | Dec 2010 Executive Summary The European Regulation on the Registration, Evaluation, Authorisation […]

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  • Tags : Animal, Assessment, cancer, chemical, Chemical safety assessments (CSA), chronic effects, chronic exposure, Compound, default AF, derived no-effect levels (DNEL), exposure, exposure scenarios (ES), Food, general population, health, Informed AF, inhalation, irritation, local effect, Lung, R.8 guidance, REACh, REACH TGD, safety assessment, skin contact, systemic effect, targeted risk assessment (TRA), Treatment, workplace
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  29 January 2009

  TR 104 – Framework for the Integration of Human and Animal Data in Chemical Risk Assessment

  TR 104 : Framework for the Integration of Human and Animal Data in Chemical Risk Assessment | January 2009 Human data form the […]

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  • Tags : Animal, animal data, approach, cancer, chemical, exposurchemical, exposure, Framework, health effect, human data, Human health, pharmaceuticals, Population, Risk, Risk assessment, task force, Toxicological
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  29 December 2007

  TR 102 – Intelligent Testing Strategies in Ecotoxicology: Mode of Action Approach for Specifically Acting Chemicals

  TR 102 : Intelligent Testing Strategies in Ecotoxicology: Mode of Action Approach for Specifically Acting Chemicals | December 2007 There is widespread regulatory […]

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  • Tags : Absorption, acute, Agrochemical, algae, amphibians, animal welfare, Antimycotic, aquatic, arthropod, Assessment, Bacteria, bioaccumulation, biochemical, biological, biomarker, biomedical, biomolecule, cancer, Carbamates, carrier protein, cellular, chemical, chronic, Compound, Crustaceans, CYP, cypermethrin, daphnid, development, developmental, drug, ecosystem, Ecotoxicity, environmental risk assessment (ERA), Enzyme, Ergosterol, exposure, fish, fluoxetine, Freshwater, Fungal, Growth, Homones, Human, Hydrophilic, in vivo testing, intelligent testing strategies (ITS), invertebrate, Ketoconazole, Lipophilic, mammalian, marine, Medication, microbial, microorganism, MOA, MOA1, MOA2, MOA3, MOA4, molecular, mollusks, neurotoxic, Neurotoxicity, neurotransmitter, NOEC, non-arthropod, Non-arthropods, Oestrogen, oestrogenic, organism, Pharmaceutical, pharmacological, Phylogeny, physical-chemical data, plant, Population, protein target ITS, reactive chemicals, Receptor, reproduction, reproductive, Risk assessment, science, Scientific, sensitivity ratio, serotonin, species, structure activity relationships, substance, survival, target, toxic effects, Toxicity, Toxicological, Triclosan, Tumour, vertebrate, vitellogenin, zebrafish
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  28 September 2006

  JACC Report 51 – Synthetic Amorphous Silica

  JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity […]

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  • Tags : Absorption, acute inhalation toxicity, adverse effects, agglomerates, airborne concentrations, alkali metal silicate, American Conference for Governmental Industrial Hygienists, amorphous silicas, aqueous systems, bioavailable, bone marrow, cancer, carcinogenicity, chromatography, chromosomal aberrations, chronic toxicity, Condensation, contact allergy, cosmetics, cracking, dermal irritation, dermal toxicity, developmental toxicity, diatoms, dichlorodimethyl, DNA synthesis, dryness, Ecotoxicology, elastomers, Emphysema, environment, Environmental fate, Epidemiology, Erythema, Excreted, experimental animals, eye irritant, Eye Irritation, fertility, focal fibrosis, Gas chromatography, genotoxic, Genotoxicity, granuloma, human risk assessment, Hydrophilic, hydrophobic, in vitro, in vivo, inhalable, inhalation, inks, International Agency for Research on Cancer, Intravenous injection, intrinsic toxicity, LOAEL, Long-term inhalation, long-term respiratory health effects, lung collagen, lung collagen content, lung inflammation. lung tumours, man-made SAS, mechanical irritation, methyl, mice, Morphology, mortality, mutagenic, natural flux, neoplasms, NOAEL, non-crystalline, non-toxic, oral, oral administration, particle size, peripheral, pharmaceuticals, pneumonia, precipitated silica, pulmonary function, pulmonary inflammation, pulmonary retention, pyrogenic silica, rats, reproductive organs, respirable, respiratory distress, SAS, SAS dust, Sex, Silica, silica gel, Silicon dioxide, silicon metal, Skin Irritation, sodium chloride, solubility, spectroscopy, subchronic, subcutaneously, Suffocation, surface treatment, survival rate, synthetic amorphous silica, thermal route, tissue reaction, toxic, Toxicology, tumours, weight gain, wet route
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  28 September 2005

  JACC Report 48 – Hexafluoropropylene

  JACC 048 : Hexafluoropropylene (CAS No. 116-15-4) | October 2005 This report has been produced as part of the ECETOC Joint Assessment of […]

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  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, atmospheric breakdown, bioaccumulate, biota, cancer, carbon dioxide, carcinogenicity, chronic toxicity, clonic spasms, closed systems, consumer exposure, developmental toxicity, developmental toxicity studies, DNA synthesis, Ecotoxicity, environment, environmental risk, exposure limit, fluoro-elastomers, Fluoropolymers, Genotoxicity, German MAK Commission, global warming, Hexafluoropropylene, HFP, hydrogen fluoride, kidney, mice, nephrotoxicity, NOAEL, occupational exposure., partition, perfluoropolyether functional fluids, photolysis, polymeric products, rats, reaction, relative kidney weight, relative spleen weight, reproductive system, Soluble, Synthesis, target organ, Tetrafluoroethylene, Toxicity, trifluoroacetic acid
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  29 March 2005

  TR 095 Vol I – The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume I

  TR 095 Vol I : The Toxicology of Glycol Ethers and its Relevance to Man (Fourth Edition) Volume I | March 2005 This […]

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  • Tags : 2-Butoxyethanol, acetic acid, apoptosis, cancer, chemical intermediates, Chemical substances, chronic toxicity, Ether, Ethylene oxide, Eye Irritation, forestomach tumours, Functional groups, Gas chromatography, glycine, Glycol ethers, hypersensitivity, Occupational safety and health, Propylene glycol, solvent applications
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  29 November 2001

  TR 081 – Human Acute Intoxication from Monochloroacetic Acid: Proposals for Therapy

  TR 081 : Human Acute Intoxication from Monochloroacetic Acid: Proposals for Therapy | November 2001 The industrial chemical monochloroacetic acid (MCAA) is used […]

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  • Tags : cancer, cardiovascular shock, central nervous system, cerebral lactic acidosis, cerebrospinal fluid, coma, Corrosive, decontamination, dermal exposure, dichloroacetate, MCAA poisoning, metabolic acidosis, Monochloroacetic Acid, necrosis, Oral exposure, phenobarbitone, sodium bicarbonate solution, systemic intoxication, systemic poisoning, toxic effects, Toxicology, Trichloroacetic acid