bioaccumulation

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  22 January 2014

  TR 123 – Environmental risk assessment of ionisable compounds

  SCIENCE NEWS FLASH: New ECETOC report addresses environmental exposure assessment of ionisable organic compounds When predicting the concentration of an ionisable chemical in […]

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  • Tags : acetic acid, active pharmaceutical ingredients, analytical equipment, analytical methods, analytical technology, apparent chemical equilibrium concentration, Aquatic toxicity, atracurium besylate, bioaccumulation, Bioavailability, Bioconcentration, biodegradation, biodegradation test systems, bupropion hydrochloride, chemical reactivity parameters, chemical safety assessment, chemical specific kinetic data, chemical substance information, chlorpheniramine maleate, clobetasol propionate, computional methods, data retrieval systems, doxepin hydrochloride, ecotoxicilogical testing, encvironmetal risk, environment, exposure assessment tool, gemfibrozil, human and veterinary pharmaceuticals, hydolysis, ionisable chemicals, ionisable organic chemical, ionisable organic compounds, measured physical chemical property data, medicinal product, Metformin hydrochloride, multimedia models, Paroxetine hydrochloride, personal care products, pharmaceutical chemicals, pharmaceutical compounds, pharmaceutical products, pharmaceutical residues, pharmaceuticals, pharmaceuticals estrogens, physical chemical and biological properties, physical chemical hydrolysis, physical chemical property data, propranolol hydrochloride, quantative structure activity, risk assessment tools, risk management, ropinirole hydrochloride, Rosiglitazone maleate, substance property data, test protocols, testing, TGD framework, valacyclovir hydrochloride, veterinary medicinal products, veterinary pharmaceuticals, vinorelbine tartrate, wastewater treatment systems
• 29 December 2007

  TR 102 – Intelligent Testing Strategies in Ecotoxicology: Mode of Action Approach for Specifically Acting Chemicals

  TR 102 : Intelligent Testing Strategies in Ecotoxicology: Mode of Action Approach for Specifically Acting Chemicals | December 2007 There is widespread regulatory […]

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  • Tags : Absorption, acute, Agrochemical, algae, amphibians, animal welfare, Antimycotic, aquatic, arthropod, Assessment, Bacteria, bioaccumulation, biochemical, biological, biomarker, biomedical, biomolecule, cancer, Carbamates, carrier protein, cellular, chemical, chronic, Compound, Crustaceans, CYP, cypermethrin, daphnid, development, developmental, drug, ecosystem, Ecotoxicity, environmental risk assessment (ERA), Enzyme, Ergosterol, exposure, fish, fluoxetine, Freshwater, Fungal, Growth, Homones, Human, Hydrophilic, in vivo testing, intelligent testing strategies (ITS), invertebrate, Ketoconazole, Lipophilic, mammalian, marine, Medication, microbial, microorganism, MOA, MOA1, MOA2, MOA3, MOA4, molecular, mollusks, neurotoxic, Neurotoxicity, neurotransmitter, NOEC, non-arthropod, Non-arthropods, Oestrogen, oestrogenic, organism, Pharmaceutical, pharmacological, Phylogeny, physical-chemical data, plant, Population, protein target ITS, reactive chemicals, Receptor, reproduction, reproductive, Risk assessment, science, Scientific, sensitivity ratio, serotonin, species, structure activity relationships, substance, survival, target, toxic effects, Toxicity, Toxicological, Triclosan, Tumour, vertebrate, vitellogenin, zebrafish
• 29 January 2006

  TR 098 – Risk Assessment of PBT Chemicals

  TR 098 : Risk Assessment of PBT Chemicals | December 2005 Many chemical regulatory schemes exist around the world that contain hazard-based criteria […]

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  • Tags : adverse effects, bioaccumulation, bioaccumulative and toxic chemicals, chemical management, Ecotoxicology, effects assessments, endocrine disrupting chemicals, environmental safety, Exposure assessment, hazardous chemicals, hydrophobic chemicals, long-term exposure, Persistent, Risk assessment, sorption, Toxicology, Trichloroethylene, very persistent very bioaccumulative chemicals, wastewater treatment
• 28 January 2006

  JACC Report 50 – 1,1,1,2-Tetrafluoroethane (HFC-134a) Second edition

  JACC 050 : 1,1,1,2-Tetrafluoroethane (HFC-134a) (CAS No. 811-97-2) (Second Edition) | January 2006 This report has been produced as part of the ECETOC […]

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  • Tags : 1 1 1 2-Tetrafluoroethane, Acute toxicity, adrenaline, adverse effects, air-conditioning, aquatic environment, Aquatic organisms, atmospheric concentration, Atmospheric degradation, atmospheric lifetime, bioaccumulation, biodegradation, biota, body weight gain, bromine, carbon dioxide, Cardiac sensitisation, cell adenoma, chemical, chemical properties, chlorine, Chlorofluorocarbon, chronic toxicity, control groups, corn oil, degradation, DNA synthesis, Ecotoxicity, environment, Environmental fate, Epinephrine, experimental animals, expired air, Eye Irritation, female rats, fertility, formic acid, gas, genotoxic, global warming potential, greenhouse effect, haematology, HFC-134a, hydrochlorofluorocarbons, hydrofluoric acid, hydroxyl radicals, hyperplasia, in vitro, in vivo, inhalation, irritation, male rats, Metabolism, metered dose inhalers, non flammable gas, non-neoplastic, occupational exposure., Ozone depletion, PAFT, partition, Programme for Alternative Fluorocarbon Toxicity Testing, Propellants, rats, Refrigeration, reproductive effects, Sex, Skin Irritation, Skin sensitisation, skin sensitiser, soil, sorption, spectroscopy, teratogenic, testicular Leydig, testicular Leydig cell hyperplasia, testosterone, Toxicity, trifluoroacetic acid, Troposphere, tumours
• 28 November 2005

  JACC Report 49 – Vinylidene Fluoride

  JACC 049 : Vinylidene Fluoride (CAS No. 75-38-7) | November 2005 This report has been produced as part of the ECETOC Joint Assessment […]

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  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, Assessment, atmosphere, Atmospheric degradation, bioaccumulation, biodegradation, biomagnification, body weight, breakdown, carbon dioxide, Carbonyl fluoride, Cardiac sensitisation, chlorotrifluoroethylene, citric acid cycle, clinical chemistry, colourless odourless flammable gas, copolymers, depletion, Ecotoxicity, embryotoxic, environment, Environmental fate, Environmental protection agency, EPA, exposure, Eye Irritation, fertility, fluoroacetic acid, foetotoxic, foetotoxic or teratogenic effect, food chain, formaldehyde, global warming, ground-level ozone, haematology, Hexafluoropropylene, HFC-143a, high volatility, Histopathology, hydroxyl radicals, impaired spermatogenesis, in vitro, in vivo, inhalation studies, kidneys, limited solubility, lipomas, liposarcomas, mineralisation, Mouse, NOAEL, organ weights, partition, polyvinylidene fluoride, rats, regenerative changes, reproduction, Rhinitis, Sex, soil, Soluble, stratospheric ozone, teratogenic, teratology study, Terrestrial organisms, testes, Tetrafluoroethylene, toxic, Toxicity, Troposphere, tropospheric ozone, urinary fluoride excretion, VDF, vinylidene fluoride, vomeronasal organ
• 20 February 2005

  TR 094 – Whole Effluent Assessment

  TR 094 : Whole Effluent Assessment | February 2005 There is increasing recognition by regulators that there are limitations to the substance-specific approach […]

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  • Tags : Acute toxicity, bioaccumulation, biological monitoring, biomarkers, chemical monitoring, chronic toxicity, contaminants, ecosystems, effluent assessment, effluent components, effluent testing, effluents, Environmental fate, OSPAR, Persistence, Risk assessment, sorption, stressors, substance-oriented approach, substance-specific approach, test species, Toxicology, wastewater treatment, Water Framework Directive, WEA, WET, WFD, whole effluent assessment, whole effluent toxicity
• 28 December 2003

  Special Report 17 – Risk Assessment Report for Existing Substances Methyl tertiary-Butyl Ether

  SR 17 : Risk Assessment Report for Existing Substances Methyl tertiary-Butyl Ether | December 2003 Methyl tertiary-butyl ether (MTBE) has been prioritised for […]

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  • Tags : Absorption, Antibodies, bioaccumulation, Biodegradable, carcinogen, chemical intermediate, chemical synthesis, chronic toxicity, CNS depression, DNA synthesis, dose groups, Ethyl tert-butyl ether, existing substances, exposure, follicular cell adenoma, formaldehyde, Gas chromatography, Genotoxicity, hepatocellular adenoma, human health risk assessment, irritation, Isobutylene, leukaemia, Liquid, Methyl tert-butyl ether, methyl tertiary butyl, methyl tertiary-Butyl Ether, organic chemicals, oxygenated gasoline, physico-chemical properties, pulmonary elimination, Risk assessment, risk reduction measures, sensory irritation, test protocol, toxicokinetics, treatment groups, vapour recovery systems, wastewater treatment
• 29 October 2003

  TR 090 – Persistence of Chemicals in the Environment

  TR 090 : Persistence of Chemicals in the Environment | October 2003 This review considers the current definition of persistence of chemicals in […]

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  • Tags : abiotic, Aeration, aquatic systems, bioaccumulation, biodegradation tests, biodegradative potential, biomass levels, biotic, chemical concentration, chemical persistence, chemical property estimation methods, cometabolism, Default half-life, degradation, environmental persistence, Environmental risk assessment, Half-life, inoculum, metabolite, micro-organisms, multi media models, organic chemicals, overall half-life, overall persistence, parent compound, PBT, Persistence, Single medium half-life, sorption, spectroscopy, testing strategy, Toxicity, Toxicology
• 29 September 2003

  TR 089 – (Q)SARs: Evaluation of the commercially available software for human health and environmental endpoints with respect to chemical management applications

  TR 089 : (Q)SARs: Evaluation of the commercially available software for human health and environmental endpoints with respect to chemical management applications | […]

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  • Tags : (Q)SARS, Acute toxicity, Ames test, animal testing, bioaccumulation, Bioconcentration factor, chemical biological interactions, chemical hazard, chemical structure, Ecotoxicology, Environmental fate, environmental health perspectives, EU Chemicals Policy, Hazard assessment, high production volume, HPV, In silico approaches, organic chemicals, prediction systems, product development, Regulation of chemicals, Risk assessment, Simplified mathematical representations, sorption, white paper
• 29 December 2002

  TR 084 – Scientific Principles for Soil Hazard Assessment of Substances

  TR 084 : Scientific Principles for Soil Hazard Assessment of Substances | July 2002 This report reviews the scientific principles that should underpin […]

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  • Tags : aquatic environment, Assessment, bioaccumulation, Bioavailability, dose-response curve, Ecotoxicology, equilibrium partitioning, intrinsic toxicity, long-term effects, modifying factors, nutrient solution, soil hazard classification, surrogate data, terrestrial hazard classification, terrestrial test guidelines, toxicity classes, wastewater treatment