Special Report 19

CASE STUDIES FOR AOP DEVELOPMENT

A Developmental Toxicity Ontology (DTO) was built for the purposes of these case studies. The DTO builds upon the Adverse Outcome Pathway Ontology (AOPO)[1]. AOPO builds upon the Bioassay Ontology (BAO)[2], the Human Phenotype Ontology (HPO)[3], and the Chemical Entities of Biological Interest Ontology (ChEBI)[4], as well as their dependencies.

[1] AOPO: https://github.com/DataSciBurgoon/aop-ontology
[2] BAO: http://bioassayontology.org/
[3] HPO: https://bioportal.bioontology.org/ontologies/HP
[4] ChEBI: https://www.ebi.ac.uk/chebi/

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