Technical Report 122

ABBREVIATIONS

ACGIH
American conference of governmental industrial hygienists
AF
Assessment factor
AM
Alveolar macrophage
AOP
Adverse outcome pathway
BAL
Bronchoalveolar lavage
BALF
Bronchoalveolar lavage fluid
BAT
Biological tolerance value for occupational exposure
BET
Brunauer-Emmet-Teller
BOELV
Binding occupational exposure limits value
BrdU
Bromodeoxyuridine
CB
Carbon black
CLP
Classification, labelling and packaging of substances and mixtures
CWP
Coal workers pneumoconiosis
DNA
Deoxyribonucleic acid
DNEL
Derived no effect level
DR
Dose rate
ECHA
European Chemicals Agency
EU
European Union
fD
Fluorescence detection
GHS/CLP
Globally harmonised system of classification and labelling of chemicals
HEC
Human equivalent concentration
HPRT
Hypoxanthine phosphoribosyltranferase

HRTM
Human respiratory tract dosimetry model
I
Index
IARC
International Agency for Research on Cancer
ICRP
International Commission on Radiological Protection
ILSI
International Life Sciences Institute
IOELVs
Indicative occupational exposure limits values
IPCS
International programme on chemical safety
IUPAC
International Union of Pure and Applied Chemistry
KSC
Keratinising squamous-cell
LDH
Lactate dehydrogenase
LOAECs
Lowest observed adverse effect concentration
LOAEL
Lowest observed adverse effect level
MAK
Maximum workplace concentration (Maximale Arbeitsplatzkonzentration)
MMAD
Mass median aerodynamic diameter
MoA
Mode of action
MPPD-model
Multiple path particle dosimetry model
NMRD
Nonmalignant respiratory disease
mRNA
Messenger RNA
MWCNT
Multiwalled carbon nanotube
NADPH
Nicotinamide adenine dinucleotide phosphate
NOAEC
No observed adverse effect concentration
NOAEL
No observed adverse effect level
NTP
National toxicology program
OECD
Organisation for economic co-operation and development

OEL
Occupational exposure limits
OPPTS
(US EPA’s) office of prevention, pesticides and toxic substances
PAR
Proximal aveolar region
PMN
Polymorphonuclear leukocyte
PNOR
Particulates not otherwise regulated
PSP
Poorly soluble particle
REACH
Registration, evaluation, authorisation and restriction of chemicals
RMV
Respiratory minute volume
RNS
Reactive nitrogen species
ROS
Reactive oxygen species
RR
Relative risk
SAS
Synthetic amorphous silica
SCOEL
Scientific committee on occupational exposure limits
SMRs
Standardised mortality ratios
STOT-RE
Specific target organ toxicant-repeated exposure
Ti
Tolerable intake
TEM
Transmission electron microscopy
TGF
Transforming growth factor
TWA
Time-weighted average
UF
Uncertainty factor
UFP
Ultrafine particles
WG
Water-dispersible granule
ZnO
Zinc oxide