Objective: Put the presumed associations between chemicals in the environment and disease into their proper scientific perspective. The focus is particularly directed towards rigorous methodology in observational epidemiology.

Current activities:

Task Force on Carcinogenicity of formaldehyde

Childhood asthma and contributing factors (commissioned review)

Monitoring of an LRI project: Reprogramming of DNA methylation during mammalian development and environmental impact of endocrine disruptors

Monitoring of an LRI project: Assessment of risk factors influencing trends in incidence of female breast carcinoma

Establishment of observational epidemiological studies register

Recent publications and completed activities:

Workshop Report 18: The enhancement of the scientific process and transparency of observational epidemiology studies (2009)

Technical Report 105: Evaluation of cardiac sensitisation test methods (2009)

Technical Report 104: Framework for the integration of human and animal data in chemical risk assessment (2009)

Technical Report 96: Trends in children's health and the role of chemicals: state of the science review (2005)