Workshop Report 27


Beausoleil C, Ormsby JN, Gies A, Hass U, Heindel JJ, Holmer ML, Nielsen PJ, Munn S, Schoenfelder G. 2013. Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary. Chemosphere pii:S0045-6535(13)00885-0.

Boobis A, Budinsky R, Collie S, Crofton K, Embry M, Felter S, Hertzberg R, Kopp D, Mihlan G, Mumtaz M, Price P, Solomon K, Teuschler L, Yang R, Zaleski R. 2011. Critical analysis of literature on low-dose synergy for use in screening chemical mixtures for risk assessment. Crit Rev Toxicol 41(5):369-383.

ECETOC. 2012. Effects of chemical co-exposures at doses relevant for human safety assessment. Technical Report No. 115. European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels, Belgium.

EFSA. 2012. EFSA Scientific Colloquium XVII. Low-dose-response in toxicology and risk assessment, Parma, 14-15 June 2012. Advanced Draft Summary Report.

EFSA. 2013. Scientific opinion on the hazard assessment of endocrine disruptors: Scientific criteria for identification of endocrine disruptors and appropriateness of existing test methods for assessing effects mediated by these substances on human health and the environment. European Food Safety Authority, Parma, Italy. EFSA Journal 11(3):3132.

EU. 2011. Opinion of SCHER, SCCS, SCENIHR on the Toxicity and Assessment of Chemical Mixtures. Available at:

Kortenkamp A, Martin O, Faust M, Evans R, McKinlay R, Orton F, Rosivatz E. 2011. State of the Art assessment of endocrine disrupter. Project Contract Number 070307/2009/550687/SER/D3. Final Report to the Directorate General for the Environment, EU Commission.

UNEP/WHO. 2013. State of the science of endocrine disrupting chemicals – 2012. Prepared by Bergman A, Heindel JJ, Jobling S, Kidd KA, Zoeller RT, eds, for the United Nations Environment Programme and World Health Organization. Available at:

Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, Shioda T, Soto AM, vom Saal FS, Welshons WV, Zoeller RT, Myers JP. 2012. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev 33(3):378-455.

Zoeller RT, Brown TR, Doan LL, Gore AC, Skakkebaek NE, Soto AM, Woodruff TJ, Vom Saal FS. 2012. Minireview: Endocrine-disrupting chemicals and public health protection: a statement of principles from the endocrine society. Endocrinology 153 (9):1-14.