Monographs

Monographs are comprehensive reviews of generic topics or issues fundamental to the application of sound science in evaluating the hazards and risks of chemicals to human health and the environment.

• DOC 043 - Contact sensitisation Classification according to potency. A commentary.

  07/2003

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• Mono 001 - Good Laboratory Practice

  10/1979

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• Mono 002 - A Contribution to Strategy for Identification and Control of Occupational Carcinogens

  09/1980

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• Mono 003 - Risk Assessment of Occupational Chemical Carcinogens

  05/1985

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• Mono 004 - Hepatocarcinogenesis in Laboratory Rodents: Relevance for Man

  10/1982

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• Mono 005 - Identification and Assessment of the Effects of Chemicals on Reproduction and Development (Reproductive Toxicology)

  12/1983

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• Mono 006 - Acute Toxicity Tests, LD50 (LC50) Determinations and Alternatives

  05/1985

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• Mono 007 - Recommendations for the Harmonisation of International Guidelines for Toxicity Studies

  12/1985

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• Mono 009 - Assessment of Mutagenicity of Industrial and Plant Protection Chemicals

  06/1987

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• Mono 010 - Identification of Immunotoxic Effects of Chemicals and Assessment of their Relevance to Man

  08/1987

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• Mono 011 - Eye Irritation Testing

  06/1988

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• Mono 012 - Alternative Approaches for the Assessment of Reproductive Toxicity (with emphasis on embryotoxicity/teratogenicity)

  11/1989

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• Mono 013 - DNA and Protein Adducts: Evaluation of their Use in Exposure Monitoring and Risk Assessment

  10/1989

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• Mono 014 - Skin Sensitisation Testing

  03/1990

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• Mono 015 - Skin Irritation

  07/1990

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• Mono 018 - Evaluation of the Neurotoxic Potential of Chemicals

  09/1992

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• Mono 019 - Respiratory Allergy

  08/1993

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• Mono 020 - Percutaneous Absorption

  08/1993

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• Mono 021 - Immunotoxicity: Hazard Identification and Risk Characterisation

  09/1994

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• Mono 022 - Evaluation of Chemicals for Oculotoxicity

  11/1994

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• Mono 024 - Risk Assessment for Carcinogens

  07/1996

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• Mono 025 - Practical Concepts for Dose Selection in Chronic Toxicity and Carcinogenicity Studies in Rodents

  02/1996

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• Mono 026 - Aquatic Toxicity Testing of Sparingly Soluble, Volatile and Unstable Substances

  09/1996

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• Mono 027 - Aneuploidy

  08/1997

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• Mono 028 - Threshold-Mediated Mutagens -- Mutation Research Special Issue

  01/2000

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• Mono 029 - Skin Sensitisation Testing for the Purpose of Hazard Indentification and Risk Assessment

  09/2000

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• Mono 031 - Guidance on Evaluation of Reproductive Toxicity Data

  02/2002

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• Mono 032 - Use of Human Data in Hazard Classification for Irritation and Sensitisation

  07/2002

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• Mono 033 - Application of Physiological - Toxicokinetic Modelling to Health Hazard Assessment of Chemical Substances

  02/2003

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• Mono 034 - Toxicogenomics in Genetic Toxicology and Hazard Determination

  08/2005

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• Mono 035 - Biomarkers and molecular epidemiology

  08/2006

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• Mono 036 - Environmental Genotoxins in Children and Adults

  08/2006

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• Mono 037 - Biomarkers in Children and Adults

  07/2007

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