Chinese
French
German
Italian
Japanese
Spanish
PDF and printed versions of reports:
Please note that, as part of our continuing drive for efficiency and environmental care, all ECETOC publications are now distributed exclusively in electronic format.
Reports can be downloaded free of charge in PDF format from our website: see download buttons in the main publication lists and at the bottom of the abstracts and summaries.
ECETOC articles can be obtained via the publishers' websites and off-prints can be requested from the Secretariat (for members, where copyright allows). For these reasons, clicking the download link for an ECETOC article will result in a mail being sent to you with a link to the publisher's website.
www.ecetoc.org/publications
- 1.7.1: Technical Reports
- 1.7.2: Monographs
- 1.7.3: JACC Reports
- 1.7.4: Special Reports
Current page is 1.7.5: Workshop Reports
- 1.7.6: Documents
- 1.7.7: ECETOC Articles
- 1.7.9: Annual Reports
review the progress made on the application of ?omics technologies to chemical safety and assess the potential impact of these new technologies on the risk assessment of chemical substances.
Background
The aim of the workshop was to review the progress made on the application of ?omics technologies to chemical safety and assess the potential impact of these new technologies on the risk assessment of chemical substances.
In particular the workshop addressed the following points:
1. Conditions to generate ?omics data relevant to toxicity (appropriate study design, quality control, exploitation and interpretation of data).
2. Usefulness of ?omics technologies in predicting toxicity in mammalian and non-mammalian models.
3. Usefulness of ?omics technologies in elucidating mechanism of action leading to toxicity.
4. Sensitivity of the ?omics technologies in detecting changes related to toxicity and comparison with sensitivity from more traditional methods (histopathology, enzyme assays, hormone measurements?).
5. What do regulators expect in terms of data quality when technical dossiers are submitted: How many positives, how many negatives, data variability?
The workshop was limited to participation by selected industry experts and invited external scientists.
[ Download ]
