Quick links:
Task Forces Workshops Workshops Cefic LRI  Twitter

 

Upcoming events
Latest publications
ECETOC at a glance

Established in 1978, ECETOC is Europe’s leading industry association for developing and promoting top quality science in human and environmental risk assessment of chemicals.  Members include the main companies with interests in the manufacture and use of chemicals, biomaterials and pharmaceuticals, and organisations active in these fields.  ECETOC is the scientific forum where member company experts meet and co-operate with government and academic scientists, to evaluate and assess the available data, identify gaps in knowledge and recommend research, and publish critical reviews on the ecotoxicology and toxicology of chemicals, biomaterials and pharmaceuticals.

ECETOC also provides scientific representation for its member companies through presentations at specialist meetings and by participation in the scientific activities of international agencies, government authorities and professional societies.  A non-profit, non-commercial and non-governmental organisation, ECETOC prides itself on the objectivity and integrity of its work programme, the output of which is published in the form of peer-reviewed reports and articles in peer-reviewed journals, or as specialised workshops.

Read in more detail here.

ECETOC is governed by a Board of Administration comprising senior executives from member companies. The Board is responsible for the overall policy and finance of the organisation and appoints the Secretary General, who oversees the day-to-day running of the organisation, and the members of the Scientific Committee which defines, manages and peer reviews the ECETOC work programme.

Select the appropriate box below for more specific information on ECETOC's organisational structure:

modus operandi

ECETOC’s approach

ECETOC believes that by identifying developing issues at their nascence, the chemicals industry will be better placed to undertake the appropriate scientific initiatives. An over-arching science strategy serves to guide ECETOC’s science programme and uses an issues, rather than activity-based approach.

What does it involve?

The premise of this strategy is that ECETOC plays an integral role in science in society. Its particular remit is to contribute objective scientific evidence to the debate about the role of chemicals in the causality of disease and assure the process of risk assessment of these chemicals.

It does so via the pursuit of the following 5 broad themes:

    Presence of chemicals in humans
    Presence of chemicals in the environment
    Effects on humans and ecosystems
    Methods
    Science of risk assessment.

This science strategy is also used as a basis for working with other stakeholders, such as academia, regulators, associations and international institutions to ensure that objective scientific evidence is used to provide the highest quality risk assessment of chemical products that minimises wherever possible the use of animals in testing.

2011 Revisions to the science strategy

The science strategy has served ECETOC well over the last years, and has been used as a guide for discussing our work programme within the Scientific Committee and with our Member Companies. Since then, new challenges have come up for the chemical industry, both on science and on the regulatory front. Issues are becoming increasingly more complex, but at the same time we are confronted with a diminishing resource of specialists in the industry that can address them. Therefore the Board and the Scientific Committee decided to review ECETOC's strategy, including the science strategy, at the 2010 Annual Technical Meeting.

Since then the ideas which the meeting produced have been developed by the Board and the Scientific Committee. These include new ways of using the scientific resources at ECETOC's disposal and ways to increase added value for members. The Strategic Science Areas concept has served us well and provided a focus for the Scientific Committee. It has allowed us to monitor the balance of our portfolio of activities and to ensure that areas which were identified as strategic were receiving sufficient attention. After three years in operation it was felt useful to reassess whether these SSA's were still appropriate.

As a result of this analysis, the following decisions were adopted:

  1. Sensitive sub-populations will no longer be a separate SSA as it is considered that the area where ECETOC has been most involved, children's health, is covered under reproductive health.
  2. Indoor air should also no longer be an SSA as we are unable to define clear activities for Task Forces.
  3. The SSA ‘omics should be merged into testing strategies, as it is now becoming integrated into more mainstream toxicology research, if not yet into any testing requirements.
  4. The two SSA's entitled ‘Biodiversity and Ecosystems' and ‘Science in Society' were considered important, but the ideas behind them were insufficiently concrete for them to be readily understood by the membership. Further work will be required to give substance to these concepts.

Accordingly, from May 2011, ECETOC pursues the following 10 strategic science areas:

Presence of chemicals in humans.

Chemicals in human tissue

Chemicals in human tissue
Objective:
Ensure that the results of biomonitoring studies are placed into appropriate context within risk assessment to human health.

Mixtures

Mixtures and co-exposure
Objective:
Contribute to the development of a pragmatic, realistic, and science-based framework for the risk assessment of chemical mixtures.

Presence of chemicals in the environment

Assessment of environmental fate and behaviour

Assessment of environmental fate and behaviour
Objective:
Develop the understanding of environmental processes that drive the fate and behaviour of chemicals and the role of these processes in risk assessment.

Effects in humans and ecosystems

Reproductive health

Reproductive health
Objective:
Ensure that the methods and the testing strategy to identify and characterise developmental and reproductive toxicants are appropriate and optimised.

Biodiversity and ecosystems

Biodiversity and ecosystems
Objective:
Identify the key science issues relevant to risk assessment of chemicals in the environment in a way that is relevant to the potential impact on biodiversity of aquatic and terrestrial ecosystems.

Methods

Integrated testing strategies Integrated testing strategies
Objective:
Contribute to a more effective approach to hazard and risk assessment. This should also support the further development and application of alternative approaches to hazard assessment, and thereby improve the workability of REACH. Good ITS approaches can reduce cost and use of animals while providing best quality data for the risk assessment process.
Risk assessment of nanomaterials

Risk assessment of nanomaterials
Objective:
Develop a series of approaches for addressing health and environmental effects of nanomaterials.

Science of risk assessment

Role of chemicals in the causality of disease

Role of chemicals in the causality of disease
Objective:
Put the presumed associations between chemicals in the environment and disease into their proper scientific perspective. The focus is particularly directed towards rigorous methodology in observational epidemiology.

Risk, hazard and precaution

Risk, hazard and precaution
Objective:
Take into account all available scientific tools to adequately characterise risk not only based on hazard characteristics but also on exposure data and dose-response considerations.

Science in society

Science in society
Objective:
Improve public confidence in the science of risk assessment and to promote its use in public policy actions. This includes the need to counter the perceptions of bias, vested interest and lack of quality assurance of industry generated data.

 

 

(Q)SAR

(Quantitative) Structure Activity Relationship

FeDTeX

The database for fertility and developmental endpoints

PBT

Persistent Bioaccumulative Toxic

3Rs

Replacement, Refinement and Reduction of Animals in Research

FERA

Food and Environment Research Agency

PCLS

Precision Cut Lung Slices

AF

Assessment Factors

GEMCO

Generic Estuary Model for Contaminants

PDMS

Polydimethylsiloxanes

ATLA

Alternatives to Laboratory Animals

GHS

Globally Harmonized System of Classification and Labelling of Chemicals

PEC

Predicted Environmental Concentration

BCF

Bio-Concentration Factor

HC5

Hazardous Concentration for 5% of species

PEG

Partner Experts Groups

BIAC

Business and Industry Advisory Committee to the OECD

HEMT

Health Effects Monitoring Team

PNEC

Predicted No Effect Concentration

C&L

Classification and Labelling

HESI

Health and Environmental Sciences Institute

POP

Persistent Organic Pollutant

CAR

Constitutive Androstane Receptor

HETRA

Human Exposure and Tiered Risk Assessment

RAC

Risk Assessment Committee

CBB

Critical Body Burden

IARC

International Agency for Research on Cancer

REACH

EU regulatory framework for the Registration, Evaluation and Authorisation of Chemicals

CEFIC

European Chemical Industry Council

ICE

Interspecies Correlation Estimation

REACH TGD

REACH Technical Guidance Document

CSA

Chemical Safety Assessments

ICEM

International Conference on Environmental Mutagens

RepDose

The database of NOELs/LOELs in repeated dose studies

DeNaMiC

Description of the nature of the accidental misuse of chemicals and chemical products

ICOH

International Commission on Occupational Health

RfP

Request for Proposal

DG SANCO

European Commission Directorate General for Health and Consumer Affairs

IFRA

International Fragrance Association

SAR

Structure-Activity Relationship

DMEL

Derived Minimum Effect Level

IHCP

Institute for Health and Consumer Protection

SEA

Socio-Economic Assessments

DNA

Deoxyribonucleic acid

ILSI-HESI

International Life Sciences Institute - Health and Environmental Science Institute

SETAC

Society of Environmental Toxicology and Chemistry

DNEL

Derived No Effect Level

IPCS

International Programme on Chemical Safety

SIEF

Substance Information Exchange Forum

ECB

European Chemicals Bureau

ITEM

Institute of Toxicology and Experimental Medicine

SIG

LRI Strategy Implementation Group

ECHA

European Chemicals Agency

ITS

Intelligent/Integrated Testing Strategies

SSD

Species Sensitivity Distributions

ECVAM

European Centre for the Validation of Alternative Methods

JACC

Joint Assessment of Commodity Chemicals

STOTS

State of the Science Reviews

EEMS

European Environmental Mutagen Society

JRC

Joint Research Centre; The European Union's scientific and technical research laboratory and an integral part of the European Commission

SVHC

Substances of Very High Concern

EMBK

ECETOC Marine Biodegradation Kinetics database

LOEL

Lowest Observed Effect Level

TMF

Trophic Magnification Factor

EMT

Environment Monitoring Team

LRI

Cefic's Long-range Research Initiative

TRA

Targeted Risk Assessment

ENM

Engineered Nanomaterials

MoA

Mode of Action

TSCA

Toxic Substance Control Act

EPA

(US) Environmental Protection Agency

MSC

Member State Committee

TTC

Threshold of Toxicological Concern

ERA

Environmental Risk Assessment

NC3Rs

National Centre (UK) for the Replacement, Refinement and Reduction of Animals in Research

UNCED

United Nations Conference on Environment and Development

ES

Exposure Scenarios

NOEL

No Observed Effect Level

vPvB

very Persistent very Bioaccumulative

ESAC

ECVAM Scientific Advisory Committee

OECD

Organisation for Economic Cooperation and Development

WFD

EU Water Framework Directive

EU

European Union

OESC

Occupational and Environmental Exposure of Skin to Chemicals

WHO

World Health Organization

EUROTOX

Association of European Toxicologists and European Societies of Toxicology

OEH

Occupational and Environmental Health

 
EUSES

European Union System for the Evaluation of Substances

OSR

Observational Epidemiologic Studies Register

 

 Keep up to date with the latest press releases from ECETOC the easy way:

 

 

 

Follow us on Twitter

 

RSS Press feed

 

Sign up below to receive
press releases by email

 

A Press Pack is available upon request from our Communications, Media and Web Manager, Ian Cummings.

Email: ian.cummings@ecetoc.org

Tel. +32 2 663 3817

Fax. + 32 2 675 3625

Press Releases

A full list of Press Releases can be found here; subscribe to our Twitter or RSS Press feeds above to be kept up to date with news from ECETOC, or register below to receive ECETOC Press Releases by e-mail:

Name*
Job title
Organisation*
E-mail*
Comments

After submitting this form, you will be re-directed to the ECETOC home page and a confirmation mail will be sent to the e-mail address that you have provided.

 

Click here for latest Press Releases:

 

Wikio

ECETOC AISBL
Avenue Edmond Van Nieuwenhuyse 4 Bte 6
B-1160 Brussels
Belgium

Tel: +32 2 675 3600
Fax: +32 2 675 3625
Email: info@ecetoc.org

Location Map:


View Larger Map