ECETOC Workshop on Chemical Respiratory Allergy: Clinical Information and how to use it and improve it

27-28 October 2016, NH Nacional Hotel, Madrid, Spain

Aims of the Workshop

Specific Objectives:

  1. Develop best practice guidance on how to assess and use available human data for the identification and regulation of respiratory sensitizers, including the creation of a framework for the interpretation of strength of evidence and weighting.
  2. Explore opportunities to identify biomarkers for sensitisation to chemical respiratory allergens – and the use of such biomarkers for prospective monitoring of workforces to more accurately identify threshold data.


  1. Define and promote a consistent, best practice, strategy for the evaluation of available human data for respiratory sensitizers, for use by regulators in formal decision-making processes.
  2. Publish a consensus opinion on the research required for the identification of human biomarkers of chemical respiratory sensitisation, and application in prospective monitoring of workforces with the ultimate aim of refining current human threshold data to reduce uncertainty in current risk assessment approaches.

Organising Committee

Stella Cochrane (Unilever)
Andreas Flueckiger   (F. Hoffmann-La Roche)
Helmut Greim (Technical University, Munich)
Stuart Hindle (Dow)
Ian Kimber (University of Manchester)
Carlos Rodriguez (P&G)
Madeleine Laffont (ECETOC)
Alan Poole (ECETOC)

Programme and Participants





3_Axel Schnuch_Präsentation-Madrid_V2



Workshop Report

  • See also accepted manuscript in press:
    Basketter D, Poole A, Kimber I. 2017.
    Behaviour of chemical respiratory allergens in novel predictive methods for skin sensitisation.
    Regul Toxicol Pharmacol Available online 6 March 2017  [Open Access]
    Doi 10.1016/j.yrtph.2017.03.002