Background

The idea for LRI began in the USA in 1996, with the goal of responding to public and stakeholder concerns through scientific investigation. The focus is on gaps in industry's knowledge and understanding that are critical for risk assessment. The broad aim is a validated infrastructure of scientific advice on which the entire industry and regulatory bodies will draw to respond more quickly and accurately to the public's questions.


Today's LRI is jointly managed by the American Chemical Council, Japanese Chemical Industry Association, and European Chemical Council (CEFIC). The LRI sponsors research to help address some of the priorities of the European public health strategy:

- improving risk assessment of chemicals and more specifically monitoring effects of chemicals on health
- understanding the environmental factors in human health
- establishing endocrine disruption references
- and co-ordinating research, data and activities at a European level.

LRI also addresses many of the environmental objectives of the European Union, including:

- linking environmental factors to health effects
- understanding and reducing chemical risks to environment
- improving animal testing in risk assessment.

Follow the links in this diagram for more information:

ESAP R&I Programme Council LRI SIG EMT HETRA HEMT

 

Since the establishment of the Cefic Long-range Research Initiative (LRI) programme in 1998, ECETOC has been a partner organisation. In the early days, all requests for proposal (RfPs) were written following ECETOC STOTS (state of the science reviews). As LRI has developed, so the role of ECETOC has evolved. It is now slightly different, but ECETOC's scientific input remains a key to the programme's success.

Within the LRI, ECETOC has the responsibility of maintaining three 'core teams' ( health effects, human exposure & risk assessment and environment), consisting of industry scientists, who manage the scientific evaluation of applications for funding, recommend the best research proposals and monitor of the progress of selected LRI projects. In particular they are responsible for the:
  • Development of topics for research to be considered by the LRI Strategy Implementation Group (SIG). (A core team may organise a workshop with academic, government and industry scientists for this purpose.)
  • Drafting of 'requests for proposals' (RfPs) based on ideas submitted by Cefic and ECETOC stakeholders in the LRI process.
  • Setting up selection teams of industry and external experts to choose the best research proposals in response to published RfPs and making recommendations to LRI SIG concerning the funding of the proposals.
  • Establishment of scientific liaison with the selected institutions and 'monitoring' the scientific quality and progress of the projects.
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