Scope:

The goal of the CEllSens-Eco8 project was to develop a strategy to predict acute fish lethality using fish cell lines and fish embryos. Specifically, this CEFIC-LRI/UK-DEFRA supported project addressed the replacement of the fish acute toxicity test (OECD 203) by improving assay conditions and exploring various toxicological endpoints in fish cells and zebrafish embryos. Furthermore, sub-lethal endpoints were explored as pilot explorations toward alternatives for fish chronic toxicity testing.

Invitation:

The CellSens team, with the support of ECETOC and Cefic-LRI, invites all interested parties from academia, industry and regulation to explore the project results and discuss their implications in the context of a strategy to refine, reduce or replace fish tests.

This workshop takes place in the morning prior to the SETAC Europe Meeting on May 15/2011 from 8.30 to 12.00 in the Milano Convention Centre:

Milano Convention Centre
Meeting room ORANGE 3
Via Giovanni Gattamelata 5
20149 Milano (MI)
Italy

A detailed programme is shown below and can also be downloaded here. Please use the form at the bottom of this page to register your interest in attending. The registration period has been extended and registrations must now be received by the end of April 2011.

Content:

The CellSens team will lay out the project design based on the original working hypotheses and present the outcome of the research with particular focus on:

• the construction and utility of the CEllSens chemical list
  
• pitfalls in testing chemicals of varying physico-chemical properties and strategies to overcome these pitfalls
  
• results of the screening of the CEllSens top 30 chemicals with improved testing design and in light of available fish acute toxicity data
  
• the established Quality Management Handbook and Standard Operating Procedures.

Agenda for CEllSens Open Access Meeting; May 15; 8:30 - 12:00 am:

Participation:

Registration for this meeting has now closed.

The CEllSens-Eco8 team